Application
Western blot analysis of EUHMTASE using rabbit polyclonal EHMT1 (EUHMTASE1) Antibody using 293 cell lysates (2 ug/lane) either nontransfected (Lane 1) or transiently transfected with the EUHMTASE gene (Lane 2).| Product Name | EHMT1 Antibody |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | Histone-lysine N-methyltransferase EHMT1, 211-, Euchromatic histone-lysine N-methyltransferase 1, Eu-HMTase1, G9a-like protein 1, GLP, GLP1, Histone H3-K9 methyltransferase 5, H3-K9-HMTase 5, Lysine N-methyltransferase 1D, EHMT1, EUHMTASE1, GLP, KIAA1876, |
| Product description | EHMT1, also known as EUHMTASE1, is a histone methyltransferase. This protein methylates 'Lys-9' of histone H3 in vitro. H3 'Lys-9' methylation represents a specific tag for epigenetic transcriptional repression by recruiting HP1 proteins to methylated histones. EHMT1 is Probably targeted to histone H3 by different DNA-binding proteins like E2F6, MGA, MAX and/or DP1. During G0 phase, it probably contributes to silencing of MYC- and E2F-responsive genes, suggesting a role in the G0/G1 transition of the cell cycle.1) Ogawa, H., et al., Science 296(5570):1132-1136 (2002). |
| Immunogen | This EHMT1 (EUHMTASE1) antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 195-226 amino acids from the N-terminal region of human EHMT1 (EUHMTASE1). |
| Clonality | Polyclonal |
|---|---|
| Isotype | Ig |
| Host Species | Rabbit |
| Tested Applications | WB |
| For WB starting dilution is: 1:1000: |
|
| Species Reactivity | Human |
| Concentration | 1mg/ml |
| Gene Symbol | EHMT1 |
|---|---|
| Alternative Names | Histone-lysine N-methyltransferase EHMT1 211- Euchromatic histone-lysine N-methyltransferase 1 Eu-HMTase1 G9a-like protein 1 GLP GLP1 Histone H3-K9 methyltransferase 5 H3-K9-HMTase 5 Lysine N-methyltransferase 1D EHMT1 EUHMTASE1 GLP KIAA1876 |
| Molecular Weight(MW) | 141 kDa |
Application
Western blot analysis of EUHMTASE using rabbit polyclonal EHMT1 (EUHMTASE1) Antibody using 293 cell lysates (2 ug/lane) either nontransfected (Lane 1) or transiently transfected with the EUHMTASE gene (Lane 2).| Application Notes | For WB starting dilution is: 1:1000: |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures. |
| Storage Buffer | Supplied in PBS with 0.09% (W/V) sodium azide. |
