Eukaryotic translation initiation factor 2 (EIF-2)
functions in the early steps of protein synthesis by forming a
ternary complex with GTP and initiator tRNA and binding to a 40S
ribosomal subunit. EIF-2 is composed of three subunits, alpha,
beta, and gamma, with the protein encoded by this gene representing
the beta subunit. The beta subunit catalyzes the exchange of GDP
for GTP, which recycles the EIF-2 complex for another round of
initiation.1) Rajesh, K., et al. Biochem. Biophys. Res. Commun. 374(2):336-340(2008)
Immunogen
This EIF2S2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 270-299 amino acids from the C-terminal region of human EIF2S2.
Western blot analysis in MDA-MB453 cell line lysates (35ug/lane).
Application Notes
For WB starting dilution is: 1:1000:
Additional Information
Form
Liquid
Storage Instructions
Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.