Application
Immunohistochemical analysis of paraffin-embedded human breast carcinoma tissue using Elk-1 (Ab-383).| Product Name | Elk 1 Antibody |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | Mek5, Mkk5, Prkmk5, ELK1, ETS-domain protein Elk-1 |
| Product description | Elk-1 is a member of the Ets family of transcription factors and of the ternary complex factor (TCF) subfamily. Proteins of the TCF subfamily form a ternary complex by binding to the the serum response factor and the serum reponse element in the promoter of the c-fos proto-oncogene. The protein encoded by this gene is a nuclear target for the ras-raf-MAPK signaling cascade. Alternatively spliced transcript variants encoding the same protein have been found for this gene1) Xing J, et al. (1996) Science. 273 (5277): 959-963. Janknecht R, et al. (1993) EMBO J. 12 (13): 5097-5104. Marais R, et al. (1993) Cell 73: 381-393. Kortenjann M, et al. (1994) Mol Cell Biol. 14: 4815-4824. Cavigelli M, et al. (1995) EMBO J. 14: 5957-5964. Whitmarsh A J, et al. (1995) Science. 269:403-407. |
| Immunogen | Elk-1 (Ab-383) antibody was raised against a peptide sequence around aa.381~385 (T-L-S-P-I) derived from Human Elk1. |
| Clonality | Polyclonal |
|---|---|
| Host Species | Rabbit |
| Tested Applications | IHC |
| Immunohistochemistry: 1:50~1:100: |
|
| Species Reactivity | HumanMouseRat |
| Concentration | 1mg/ml |
| Purification | Affinity purified |
| Gene Symbol | ELK1 |
|---|---|
| Alternative Names | Mek5 Mkk5 Prkmk5 ELK1 ETS-domain protein Elk-1 |
| Molecular Weight(MW) | 47 kDa |
| Tissue Specificity | This antibody detects endogenous level of total Elk-1 protein. |
| Entrez Gene | 2002 |
|---|---|
| Protein Accession | NP_001107595.1 |
Application
Immunohistochemical analysis of paraffin-embedded human breast carcinoma tissue using Elk-1 (Ab-383).| Application Notes | Immunohistochemistry: 1:50~1:100: |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | Store antibody at -20˚C for up to one year. |
| Storage Buffer | Antibody supplied in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
