Application
Immunohistochemistry staining of EPHA4 in glomerulus tissue using EPHA4 Antibody.| Product Name | EPHA4 Antibody |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | EPHA4, CEK8, EK8, Ephrin type-A receptor 4, HEK8, SEK, TYRO1, TYRO1 protein tyrosine kinase, Tyrosine-protein kinase TYRO1, EPH receptor A4, EPH-like kinase 8 |
| Product description | Nak1, a NR4 Nerve Growth Factor-Like receptor, has been shown to affect the hypothalamic-pituitary axis, neuronal differentiation, neuroendocrine regulation of adrenocortical function, and T-cell apoptosis. Nak1 also is known as nuclear receptor Tr3 and is similar to mouse Nur77 and rat NGFI-B. It is encoded by one of the immediate early genes (IEG) in response to nerve growth factor and other serum growth factors. Nak1 can bind to DNA as a monomer, homodimer, or heterodimer (with retinoid X receptors). Nak1 has been shown to inhibit vascular lesion formation and could serve as a novel target in the treatment of vascular diseases. |
| Immunogen | EPHA4 antibody was raised against a peptide located in the C-Terminal domain of EPHA4 (Human). |
| Clonality | Polyclonal |
|---|---|
| Host Species | Rabbit |
| Tested Applications | ELISAIHC |
| EPHA4 antibody can be used in immunohistochemistry starting at 7.3 μg/mL.: |
|
| Species Reactivity | BatBovineDogGibbonGorillaHamsterHorseHumanMonkeyMousePigRabbitRat |
| Concentration | 1mg/ml |
| Purification | Affinity purified |
| Gene Symbol | EPHA4 |
|---|---|
| Alternative Names | EPHA4 CEK8 EK8 Ephrin type-A receptor 4 HEK8 SEK TYRO1 TYRO1 protein tyrosine kinase Tyrosine-protein kinase TYRO1 EPH receptor A4 EPH-like kinase 8 |
| Tissue Specificity | BLAST analysis of the peptide immunogen showed no homology with other human proteins. |
Application
Immunohistochemistry staining of EPHA4 in glomerulus tissue using EPHA4 Antibody.| Application Notes | EPHA4 antibody can be used in immunohistochemistry starting at 7.3 μg/mL.: |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | EPHA4 antibody should be stored long term (months) at -80 ˚C and short term (days) at 4 ˚C. As with all antibodies avoid freeze/thaw cycles. |
| Storage Buffer | PBS, 0.1% sodium azide. |
