Application
Western blot analysis of extract from JK, HUVEC, HepG2 and HeLa cells using ERAB Antibody.| Product Name | ERAB Antibody |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | ABAD, CAMR, ERAB, HCD2, MHBD, HADH2, MRPP2, MRX17, MRX31, SCHAD, MRXS10, SDR5C1, 17b-HSD10, DUPXp11.22, ABAD |
| Product description | Functions in mitochondrial tRNA maturation. Part of mitochondrial ribonuclease P, an enzyme composed of MRPP1/RG9MTD1, MRPP2/HSD17B10 and MRPP3/KIAA0391, which cleaves tRNA molecules in their 5'-ends. By interacting with intracellular amyloid-beta, it may contribute to the neuronal dysfunction associated with Alzheimer disease (AD).1) Holzmann J., Frank P., Loeffler E., Bennett K. L., Gerner C., Rossmanith W. Cell 135:462-474 (2008) |
| Immunogen | ERAB antibody was raised against a peptide sequence around aa.253~257 (L-D-G-A-I) derived from Human ERAB. |
| Clonality | Polyclonal |
|---|---|
| Host Species | Rabbit |
| Tested Applications | WB |
| Western Blot: 1:500~1:1000: |
|
| Species Reactivity | HumanMouseRat |
| Concentration | 1mg/ml |
| Purification | Affinity purified |
| Gene Symbol | HSD17B10 |
|---|---|
| Alternative Names | ABAD CAMR ERAB HCD2 MHBD HADH2 MRPP2 MRX17 MRX31 SCHAD MRXS10 SDR5C1 17b-HSD10 DUPXp11.22 ABAD |
| Molecular Weight(MW) | 27 kDa |
| Tissue Specificity | This antibody detects endogenous level of total ERAB protein. |
| Entrez Gene | 3028 |
|---|---|
| Protein Accession | NP_004484.1 |
Application
Western blot analysis of extract from JK, HUVEC, HepG2 and HeLa cells using ERAB Antibody.| Application Notes | Western Blot: 1:500~1:1000: |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | Store antibody at -20˚C for up to one year. |
| Storage Buffer | Antibody supplied in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
