ERBB-4 receptor tyrosine kinase is activated by neuregulins, nrg- 2, nrg-3, heparin-binding egf-like growth factor, betacellulin and ntak to regulate cell proliferation and differentiation. Several isoforms of the ERBB-4 receptor tyrosine kinase have been identified and differ functionally in their response to phorbol ester: they represent cleavable and noncleavable forms of the receptor. These isoforms are differentially expressed in tissues.
Immunogen
ERBB4 antibody was raised against a peptide located near the internal domain of ERBB4 (Human).
Key Feature
Clonality
Polyclonal
Host Species
Rabbit
Tested Applications
IHC
ERBB4 antibody can be used in immunohistochemistry starting at 10 μg/mL, and immunofluorescence.: