| Product Name | ESE-1 Antibody |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | Retinoblastoma, phospho-Retinoblastoma, phospho-Rb, pS811, Retinoblastoma-associated protein, p105-Rb, Rb, RB, pRb, OSRC, pp110 |
| Product description | Epithelium-specific gene regulation plays acritical role during embryogenesis, and the epithelial cell lineage is the first differentiated cell type to appear afterfertilization. Until recently, very few epithelial cell-restricted transcription factors had been described. Members of the ets transcription factor/oncogene family havebeen implicated in human carcinogenesis following the discovery of several distinctchromosomal translocations involving members of the ets family in different types of cancer. ets factors play key roles intranscriptional control of stringently regulated genes, such as genes involved intissue development, differentiation,angiogenesis, cell cycle control and cellproliferation. ESE-1 is the first member of the ets family that was found to be exclusively expressed and inducible inepithelial cells. |
| Immunogen | C-terminal sequence of human ESE-1 protein. |
| Clonality | Polyclonal |
|---|---|
| Host Species | Rabbit |
| Tested Applications | ELISAWB |
| WB:1:500~1:2000 Notes:Optimal dilutions/concentrations should be determined by the researcher. |
|
| Species Reactivity | Human |
| Concentration | 1mg/ml |
| Gene Symbol | RB1 |
|---|---|
| Alternative Names | Retinoblastoma phospho-Retinoblastoma phospho-Rb pS811 Retinoblastoma-associated protein p105-Rb Rb RB pRb OSRC pp110 |
| Entrez Gene | 5925 |
|---|---|
| Protein Accession | AAO62758.1 |
| Application Notes | WB:1:500~1:2000 Notes:Optimal dilutions/concentrations should be determined by the researcher. |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | ESE-1 antibody can be stored at 4˚C, stable for one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures. |
| Storage Buffer | PBS |
