Application
Western blot analysis of extracts from HeLa cells treated with Serum using Phospho-ETK (Tyr566) Antibody. The lane on the right is treated with the antigen-specific peptide.| Product Name | ETK (phospho Tyr566) Antibody |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | BMX, BMX NON-receptor tyrosine kinase, Bone marrow kinase BMX, Epithelial and endothelial tyrosine kinase, NTK38 |
| Product description | Non-receptor tyrosine kinase that plays central but diverse modulatory roles in various signaling processes involved in the regulation of actin reorganization, cell migration, cell proliferation and survival, cell adhesion, and apoptosis. Participates in signal transduction stimulated by growth factor receptors, cytokine receptors, G-protein coupled receptors, antigen receptors and integrins. Induces tyrosine phosphorylation of BCAR1 in response to integrin regulation. Activation of BMX by integrins is mediated by PTK2/FAK1, a key mediator of integrin signaling events leading to the regulation of actin cytoskeleton and cell motility.1) Zhang R, et al. (2003) J Biol Chem 278, 51267-76 |
| Immunogen | ETK (phospho Tyr566) antibody was raised against a peptide sequence around phosphorylation site of Tyrosine566 (D-Q-Y (p)-V-S) derived from Human ETK. |
| Modification | p-Tyr566 |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | WB |
| Western Blot: 1:500~1:1000: |
|
| Species Reactivity | HumanMouse |
| Concentration | 1mg/ml |
| Purification | Affinity purified |
| Gene Symbol | BMX |
|---|---|
| Alternative Names | BMX BMX NON-receptor tyrosine kinase Bone marrow kinase BMX Epithelial and endothelial tyrosine kinase NTK38 |
| Molecular Weight(MW) | 78 kDa |
| Tissue Specificity | The antibody detects endogenous level of ETK only when phosphorylated at tyrosine 566. |
| Entrez Gene | 660 |
|---|---|
| Protein Accession | NP_001712.1 |
Application
Western blot analysis of extracts from HeLa cells treated with Serum using Phospho-ETK (Tyr566) Antibody. The lane on the right is treated with the antigen-specific peptide.| Application Notes | Western Blot: 1:500~1:1000: |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | Store antibody at -20˚C for up to one year. |
| Storage Buffer | Antibody supplied in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
