FABP7 Antibody: FABP7 was initially isolated from a human fetal brain cDNA library and whose mRNA was expressed in adult brain and muscle tissues at low levels. The protein encoded by this gene is a member of the fatty acid binding protein (FABPs) family, a group of small, highly conserved, cytoplasmic proteins that bind long-chain fatty acids and other hydrophobic ligands. FABPs are thought to play roles in fatty acid uptake, transport, and metabolism. FABP7 is a downstream gene of the Pax6 transcription factor and has been suggested to be essential for the maintenance of neuroepithelial cells during early cortical development. More recently, FABP7 was found to be frequently expressed in melanomas. Down-regulation of FABP7 through RNAi expression could reduce in vitro cell proliferation and Matrigel invasion, suggesting that FABP7 may be a potential target for the development of diagnostic and therapeutic tools.1) Shimizu F, Watanabe TK, Shinomiya H, et al. Isolation and expression of a cDNA for human brain fatty acid-binding protein (B-FABP). Biochim. Biophys. Acta1997; 1354:24-8.
Immunogen
FABP7 antibody was raised against a 17 amino acid synthetic peptide from near the center of human FABP7. The immunogen is located within the last 50 amino acids of FABP7.
Key Feature
Clonality
Polyclonal
Isotype
IgG
Host Species
Rabbit
Tested Applications
ELISAIHC-PWB
FABP7 antibody can be used for detection of FABP7 by Western blot at 0.5 - 2 μg/mL. Antibody can also be used for immunohistochemistry starting at 5 μg/mL.:
Immunohistochemistry of FABP7 in human breast tissue with FABP7 antibody at 5 μg/mL.
Application
Western blot analysis of FABP7 in human breast tissue lysate with FABP7 antibody at (A) 0.5, (B) 1 and (C) 2 μg/mL.
Positive Control
1) Cat. No. 1311 - Human Breast Tissue Lysate
Application Notes
FABP7 antibody can be used for detection of FABP7 by Western blot at 0.5 - 2 μg/mL. Antibody can also be used for immunohistochemistry starting at 5 μg/mL.:
Additional Information
Form
Liquid
Storage Instructions
FABP7 antibody can be stored at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Storage Buffer
FABP7 Antibody is supplied in PBS containing 0.02% sodium azide.