Application
Antibody used in IHC on Human kidney.Application
Antibody used in WB on Human Thymus at 0.2-1 ug/ml.| Product Name | FADD Antibody |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | FADD, GIG3, MORT1 |
| Product description | The protein encoded by FADD is an adaptor molecule that interacts with various cell surface receptors and mediates cell apoptotic signals. Through its C-terminal death domain, this protein can be recruited by TNFRSF6/Fas-receptor, tumor necrosis factor receptor, TNFRSF25, and TNFSF10/TRAIL-receptor, and thus it participates in the death signaling initiated by these receptors. Interaction of this protein with the receptors unmasks the N-terminal effector domain of this protein, which allows it to recruit caspase-8, and thereby activate the cysteine protease cascade.1) Thomas, L.R., et al., (2004) J. Biol. Chem. 279 (31), 32780-32785. |
| Immunogen | Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human FADD. |
| Clonality | Polyclonal |
|---|---|
| Host Species | Rabbit |
| Tested Applications | ELISAIHCWB |
| FADD antibody can be used for detection of FADD by ELISA at 1:62500. FADD antibody can be used for detection of FADD by western blot at 0.5 μg/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.: |
|
| Species Reactivity | Human |
| Concentration | 1mg/ml |
| Purification | Affinity purified |
| Gene Symbol | FADD |
|---|---|
| Alternative Names | FADD GIG3 MORT1 |
| Molecular Weight(MW) | 23 kDa |
Application
Antibody used in IHC on Human kidney.
Application
Antibody used in WB on Human Thymus at 0.2-1 ug/ml.| Positive Control | 1) Cat. No. XBL-10426 - Fetal Thymus Tissue Lysate |
|---|---|
| Application Notes | FADD antibody can be used for detection of FADD by ELISA at 1:62500. FADD antibody can be used for detection of FADD by western blot at 0.5 μg/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.: |
| Form | Liquid |
|---|---|
| Storage Instructions | For short periods of storage (days) store at 4˚C. For longer periods of storage, store FADD antibody at -20˚C. As with any antibody avoid repeat freeze-thaw cycles. |
| Storage Buffer | Antibody is lyophilized in PBS buffer with 2% sucrose. Add 50 μL of distilled water. Final antibody concentration is 1 mg/mL. |
