Application
Immunohistochemistry staining of FANCG in thymus tissue using FANCG Antibody.| Product Name | FANCG Antibody |
|---|---|
| Antibody Type | Primary Antibodies |
| Product description | FANCG (also called Protein FACG or DNA-repair protein XRCC9) is involved in DNA repair, perhaps specifically with post-replication repair or a cell cycle checkpoint function. FANCG may also be implicated in interstrand DNA cross-link repair and in the maintenance of normal chromosome stability. This protein may also function as a tumor suppressor gene. FANCG belongs to the multi-subunit Fanconi Anemia (FA) complex composed of FANCA, FANCB, FANCC, FANCE, FANCF, FANCG, FANCL/PHF9 and FANCM. FANCG contains a 5-prime GC-rich untranslated region characteristic of housekeeping genes. The putative 622-amino acid protein has a leucine-zipper motif at its N-terminus. FANCG is mainly found within the nucleus although some protein is localized in the cytoplasm. This protein is highly expressed in testis and thymus and is also found in lymphoblasts. Fanconi anemia is an autosomal recessive disorder with diverse clinical symptoms, including developmental anomalies, bone marrow failure, and early occurrence of malignancies caused by defects in the FANCG gene. At the cellular level it is associated with hypersensitivity to DNA-damaging agents, chromosomal instability (increased chromosome breakage), and defective DNA repair. |
| Immunogen | FANCG antibody was raised against amino acids 1 - 12 of FANCG (Human). |
| Clonality | Polyclonal |
|---|---|
| Host Species | Rabbit |
| Tested Applications | ELISAIFIHCWB |
| FANCG antibody can be used in Western Blot, and immunohistochemistry starting at 2.5 μg/mL. | |
| Species Reactivity | ChimpanzeeHuman |
| Concentration | 1mg/ml |
| Purification | Affinity purified |
| Gene Symbol | FANCG |
|---|---|
| Alternative Names | FANCG DNA repair protein XRCC9 Fanconi anemia group G protein FAG Protein FACG XRCC9 |
Application
Immunohistochemistry staining of FANCG in thymus tissue using FANCG Antibody.| Application Notes | FANCG antibody can be used in Western Blot, and immunohistochemistry starting at 2.5 μg/mL. |
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| Form | Liquid |
|---|---|
| Storage Instructions | Store FANCG antibody at 4 ˚C or -20 ˚C. As with all antibodies avoid freeze/thaw cycles. |
| Storage Buffer | 0.02 M potassium phosphate, 0.15 M sodium chloride, pH 7.2, 0.01% sodium azide. |
