Application
Western blot analysis in NCI-H292 cell line lysates (35ug/lane).| Product Name | FAP Antibody |
|---|---|
| Antibody Type | Primary Antibodies |
| Product description | The protein encoded by this gene is a homodimeric integral membrane gelatinase belonging to the serine protease family. It is selectively expressed in reactive stromal fibroblasts of epithelial cancers, granulation tissue of healing wounds, and malignant cells of bone and soft tissue sarcomas. This protein is thought to be involved in the control of fibroblast growth or epithelial-mesenchymal interactions during development, tissue repair, and epithelial carcinogenesis.1) Rose, J.E., et al. Mol. Med. 16 (7-8), 247-253 (2010)Ospelt, C., et al. Arthritis Rheum. 62(5):1224-1235(2010) Stremenova, J., et al. Int. J. Oncol. 36(2):351-358(2010) Chen, H., et al. Exp. Mol. Pathol. 87(3):189-194(2009) Dohi, O., et al. Histopathology 55(4):432-440(2009) |
| Immunogen | This FAP antibody is generated from rabbits immunized with the protein of human FAP. |
| Clonality | Polyclonal |
|---|---|
| Isotype | Ig |
| Host Species | Rabbit |
| Tested Applications | WB |
| For WB starting dilution is: 1:1000 | |
| Species Reactivity | Human |
| Concentration | 1mg/ml |
| Purification | Protein A |
| Gene Symbol | FAP |
|---|---|
| Alternative Names | Prolyl endopeptidase FAP 170 kDa melanoma membrane-bound gelatinase Dipeptidyl peptidase FAP Fibroblast activation protein alpha FAPalpha Serine integral membrane protease SIMP Surface-expressed protease Seprase Antiplasmin-cleaving enzyme FAP so |
| Molecular Weight(MW) | 88 kDa |
Application
Western blot analysis in NCI-H292 cell line lysates (35ug/lane).| Application Notes | For WB starting dilution is: 1:1000 |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures. |
| Storage Buffer | Supplied in PBS with 0.09% (W/V) sodium azide. |
