This gene encodes a member of the immunoglobulin receptor
superfamily and is one of several Fc receptor-like glycoproteins
clustered on the long arm of chromosome 1. The encoded protein
contains immunoreceptor-tyrosine activation motifs and
immunoreceptor-tyrosine inhibitory motifs in its cytoplasmic domain
and may play a role in regulation of the immune system. Mutations
in this gene have been associated with rheumatoid arthritis,
autoimmune thyroid disease, and systemic lupus erythematosus.1) Wu, H., et al. Hum. Immunol. (2010) In press :
Immunogen
This FCRL3 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 694-720 amino acids from the C-terminal region of human FCRL3.
Fc receptor-like protein 3 FcR-like protein 3 FcRL3 Fc receptor homolog 3 FcRH3 IFGP family protein 3 hIFGP3 Immune receptor translocation-associated protein 3 SH2 domain-containing phosphatase anchor protein 2 CD307c FCRL3 FCRH3 IFGP3 IRTA3
Western blot analysis in NCI-H460 cell line lysates (35ug/lane).
Application Notes
For WB starting dilution is: 1:1000
Additional Information
Form
Liquid
Storage Instructions
Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.