The protein encoded by this gene is a member of the
fibroblast growth factor (FGF) family. FGF family members possess
broad mitogenic and cell survival activities, and are involved in a
variety of biological processes, including embryonic development,
cell growth, morphogenesis, tissue repair, tumor growth and
invasion. This protein exhibits mitogenic activity for keratinizing
epidermal cells, but essentially no activity for fibroblasts, which
is similar to the biological activity of FGF7. Studies of the mouse
homolog of suggested that this gene is required for embryonic
epidermal morphogenesis including brain development, lung
morphogenesis, and initiation of lim bud formation. This gene is
also implicated to be a primary factor in the process of wound
healing.1) Stein, J.L., et al. Neuroimage 53(3):1160-1174(2010)
Immunogen
This FGF10 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 168-197 amino acids from the C-terminal region of human FGF10.
Western blot analysis in NCI-H460 cell line lysates (35ug/lane).
Application
Western Blot at 1:2000 dilution + mouse lung lysate Lysates/proteins at 20 ug per lane.
Application Notes
For WB starting dilution is: 1:1000
Additional Information
Form
Liquid
Storage Instructions
Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.