Application
Immunohistochemistry staining of FOLH1 in human prostate carcinoma tissue using FOLH1 Antibody.| Product Name | FOLH1 Antibody |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | FOLH1, Folate hydrolase 1, GCPII, Glutamate carboxypeptidase II, Folate hydrolase, GCP2, NAALAD1, NAALAdase, NAALADase I, PSM, FGCP, FOLH, Glutamate carboxylase II, Glutamate carboxypeptidase 2, MGCP, PSMA |
| Product description | PMSA (FOLH1) is a type II transmembrane glycoprotein belonging to the M28 peptidase family. Three functionally distinct proteins are encoded, including poly-gamma-glutamate carboxypeptidase in the intestine, N-acetylated alpha-linked acidic dipeptidase 1 in the brain, and prostate- specific membrane antigen in the prostate. A mutation in the intestinal form may be associated with impaired intestinal absorption of dietary folates, resulting in low blood folate levels and consequent hyperhomocysteinemia. The form expressed in the brain may be involved in a number of pathological conditions associated with glutamate excitotoxicity. The prostate form is up-regulated in cancerous cells and is used as an effective diagnostic and prognostic indicator of prostate cancer. This gene likely arose from a duplication event of a nearby chromosomal region. |
| Immunogen | FOLH1 antibody was raised against amino acids from the C-Terminus of FOLH1 (Human). |
| Clonality | Polyclonal |
|---|---|
| Host Species | Rabbit |
| Tested Applications | WB |
| FOLH1 antibody can be used in ELISA, Western Blot, immunohistochemistry starting at 10 μg/mL, and immunoprecipitation: |
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| Species Reactivity | Human |
| Concentration | 1mg/ml |
| Purification | Affinity purified |
| Gene Symbol | FOLH1 |
|---|---|
| Alternative Names | FOLH1 Folate hydrolase 1 GCPII Glutamate carboxypeptidase II Folate hydrolase GCP2 NAALAD1 NAALAdase NAALADase I PSM FGCP FOLH Glutamate carboxylase II Glutamate carboxypeptidase 2 MGCP PSMA |
Application
Immunohistochemistry staining of FOLH1 in human prostate carcinoma tissue using FOLH1 Antibody.| Application Notes | FOLH1 antibody can be used in ELISA, Western Blot, immunohistochemistry starting at 10 μg/mL, and immunoprecipitation: |
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| Form | Liquid |
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| Storage Instructions | Store FOLH1 antibody at 4 ˚C or -20 ˚C. As with all antibodies avoid freeze/thaw cycles. |
| Storage Buffer | 10 mM PBS, pH 7.4, BSA, sodium azide. |
