The Fos gene family consists of 4 members: FOS, FOSB, FOSL1, and FOSL2. These genes encode leucine zipper proteins that can dimerize with proteins of the JUN family, thereby forming the transcription factor complex AP-1. The FOS proteins have been implicated as regulators of cell proliferation, differentiation, and transformation.The Fos gene family consists of 4 members: FOS, FOSB, FOSL1, and FOSL2. These genes encode leucine zipper proteins that can dimerize with proteins of the JUN family, thereby forming the transcription factor complex AP-1. As such, the FOS proteins have been implicated as regulators of cell proliferation, differentiation, and transformation.1) Debinski, W. (2005) Mol. Cancer Res. 3 (4), 237-249.
Immunogen
Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human FOSL1.
Key Feature
Clonality
Polyclonal
Host Species
Rabbit
Tested Applications
ELISAIHCWB
FOSL1 antibody can be used for detection of FOSL1 by ELISA at 1:312500. FOSL1 antibody can be used for detection of FOSL1 by western blot at 0.5 μg/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.:
Antibody used in IHC on Human Skin lysate at 5.0 ug/ml.
Application
Antibody used in IHC on Human Skin lysate.
Positive Control
1) Cat. No. 1205 - Jurkat Cell Lysate
Application Notes
FOSL1 antibody can be used for detection of FOSL1 by ELISA at 1:312500. FOSL1 antibody can be used for detection of FOSL1 by western blot at 0.5 μg/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.:
Additional Information
Form
Liquid
Storage Instructions
For short periods of storage (days) store at 4˚C. For longer periods of storage, store FOSL1 antibody at -20˚C. As with any antibody avoid repeat freeze-thaw cycles.
Storage Buffer
Antibody is lyophilized in PBS buffer with 2% sucrose. Add 50 μL of distilled water. Final antibody concentration is 1 mg/mL.