Transcriptional repressor. It plays an important role in the specification and differentiation of lung epithelium. Can act with CTBP1 to synergistically repress transcription but CTPBP1 is not essential. Essential transcriptional regulator of B cell development1) Hamdan F. F., Daoud H., Rochefort D., Piton A., Gauthier J., Langlois M., Foomani G., Dobrzeniecka S., Krebs M. O., Joober R., Michaud J. L. Am. J. Hum. Genet. 87:671-678 (2010)
Immunogen
FOXP1 antibody was raised against a peptide sequence around aa. 669~673 (D-E-P-V-N) derived from Human FOXP1.