Application
Antibody used in IHC on Human Skin.| Product Name | FZD4 Antibody |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | FZD4, EVR1, FEVR, FZD4S, Fz-4, FzE4, GPCR, MGC34390, Fz4, hFz4, CD344 |
| Product description | FZD4 is a member of the frizzled family. Members of this family are seven-transmembrane domain proteins that are receptors for the Wingless type MMTV integration site family of signaling proteins. Most frizzled receptors are coupled to the beta-catenin canonical signaling pathway. This protein may play a role as a positive regulator of the Wingless type MMTV integration site signaling pathway. A transcript variant retaining intronic sequence and encoding a shorter isoform has been described, however, its expression is not supported by other experimental evidence.This gene is a member of the frizzled gene family. Members of this family encode seven-transmembrane domain proteins that are receptors for the Wingless type MMTV integration site family of signaling proteins. Most frizzled receptors are coupled to the beta-catenin canonical signaling pathway. This protein may play a role as a positive regulator of the Wingless type MMTV integration site signaling pathway. A transcript variant retaining intronic sequence and encoding a shorter isoform has been described, however, its expression is not supported by other experimental evidence. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.1) Dufourcq, P., (2008) Am. J. Pathol. 172 (1), 37-49. |
| Immunogen | Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human FZD4. |
| Clonality | Polyclonal |
|---|---|
| Host Species | Rabbit |
| Tested Applications | ELISAWB |
| FZD4 antibody can be used for detection of FZD4 by ELISA at 1:312500. FZD4 antibody can be used for detection of FZD4 by western blot at 1 μg/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.: |
|
| Species Reactivity | HumanMouseRat |
| Concentration | 1mg/ml |
| Purification | Affinity purified |
| Gene Symbol | FZD4 |
|---|---|
| Alternative Names | FZD4 EVR1 FEVR FZD4S Fz-4 FzE4 GPCR MGC34390 Fz4 hFz4 CD344 |
| Molecular Weight(MW) | 60 kDa |
Application
Antibody used in IHC on Human Skin.| Positive Control | 1) Cat. No. XBL-10409 - Fetal Liver Tissue Lysate |
|---|---|
| Application Notes | FZD4 antibody can be used for detection of FZD4 by ELISA at 1:312500. FZD4 antibody can be used for detection of FZD4 by western blot at 1 μg/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.: |
| Form | Liquid |
|---|---|
| Storage Instructions | For short periods of storage (days) store at 4˚C. For longer periods of storage, store FZD4 antibody at -20˚C. As with any antibody avoid repeat freeze-thaw cycles. |
| Storage Buffer | Antibody is lyophilized in PBS buffer with 2% sucrose. Add 50 μL of distilled water. Final antibody concentration is 1 mg/mL. |
