GABA is the major inhibitory neurotransmitter in the mammalian brain where it acts at GABA-A receptors, which are ligand-gated chloride channels. Chloride conductance of these channels can be modulated by agents such as benzodiazepines that bind to the GABA-A receptor. At least 16 distinct subunits of GABA-A receptors have been identified.1) Chou, K.C. et al., (2004) Biochem. Biophys. Res. Commun. 316 (3), 636-642.
Immunogen
Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human GABRA3.
Key Feature
Clonality
Polyclonal
Host Species
Rabbit
Tested Applications
ELISAWB
GABRA3 antibody can be used for detection of GABRA3 by ELISA at 1:312500. GABRA3 antibody can be used for detection of GABRA3 by western blot at 2.5 μg/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.:
GABRA3 antibody can be used for detection of GABRA3 by ELISA at 1:312500. GABRA3 antibody can be used for detection of GABRA3 by western blot at 2.5 μg/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.:
Additional Information
Form
Liquid
Storage Instructions
For short periods of storage (days) store at 4˚C. For longer periods of storage, store GABRA3 antibody at -20˚C. As with any antibody avoid repeat freeze-thaw cycles.
Storage Buffer
IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.Store at -20 °C.Stable for 12 months from date of receipt