Application
Western blot analysis of lysed extracts from PC12 cells using GABRB1 (Ab-434).| Product Name | GABRB1 Antibody |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | GABA(A) receptor, GABA(A)R beta-1, GBRB1, GABA-RB |
| Product description | The gamma-aminobutyric acid (GABA) A receptor is a multisubunit chloride channel that mediates the fastest inhibitory synaptic transmission in the central nervous system. This gene encodes GABA A receptor, beta 1 subunit. It is mapped to chromosome 4p12 in a cluster comprised of genes encoding alpha 4, alpha 2 and gamma 1 subunits of the GABA A receptor. Alteration of this gene is implicated in the pathogenetics of schizophrenia.1) Collins AL, et al. (2006) Neurogenetics ;7 (3): 167-174. Ma DQ, et al. (2005) Am J Hum Genet ;77 (3): 377-388. Edenberg HJ, et al. (2004) Am J Hum Genet ;74 (4): 705-714. |
| Immunogen | GABRB1 (Ab-434) antibody was raised against a peptide sequence around aa.432~436 (R-A-S-Q-L) derived from Human GABRB1. |
| Clonality | Polyclonal |
|---|---|
| Host Species | Rabbit |
| Tested Applications | WB |
| Western Blot: 1:500~1:1000: |
|
| Species Reactivity | HumanMouseRat |
| Concentration | 1mg/ml |
| Purification | Affinity purified |
| Gene Symbol | GABRB1 |
|---|---|
| Alternative Names | GABA(A) receptor GABA(A)R beta-1 GBRB1 GABA-RB |
| Molecular Weight(MW) | 54 kDa |
| Tissue Specificity | This antibody detects endogenous level of total GABRB1 protein. |
| Entrez Gene | 2560 |
|---|---|
| Protein Accession | NP_000803.2 |
Application
Western blot analysis of lysed extracts from PC12 cells using GABRB1 (Ab-434).| Application Notes | Western Blot: 1:500~1:1000: |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | Store antibody at -20˚C for up to one year. |
| Storage Buffer | Antibody supplied in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
