The product of this gene belongs to the ligand-gated ionic
channel (TC 1.A.9) family. It encodes the gamma-aminobutyric acid
(GABA) A receptor which is a multisubunit chloride channel that
mediates the fastest inhibitory synaptic transmission in the
central nervous system. This gene encodes an epsilon subunit. It is
mapped to chromosome Xq28 in a cluster comprised of genes encoding
alpha 3, beta 4 and theta subunits of the same receptor.
Alternatively spliced transcript variants have been identified, but
only one is thought to encode a protein.1) Pinheiro, A.P., et al. Am. J. Med. Genet.Neuropsychiatr. Genet. 153B (5), 1070-1080 (2010) :
Immunogen
This GABRE antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 66-94 amino acids from the N-terminal region of human GABRE.
Western blot analysis in 293 cell line lysates (35ug/lane).
Application Notes
For WB starting dilution is: 1:1000:
Additional Information
Form
Liquid
Storage Instructions
Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.