Application
Antibody used in IHC on Human Prostate Cancer at 2 ug/ml.Application
Antibody used in IHC on Human Prostate Cancer at 2 ug/ml.Application
Antibody used in IHC on Human Prostate Cancer at 2 ug/ml.Application
Antibody used in WB on Human HepG2 at 0.2-1 ug/ml.| Product Name | GADD45B Antibody |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | GADD45B, DKFZP566B133, GADD45BETA, MYD118 |
| Product description | The function of GADD45B is involved in the regulation of growth and apoptosis.This gene is a member of a group of genes whose transcript levels are increased following stressful growth arrest conditions and treatment with DNA-damaging agents. The genes in this group respond to environmental stresses by mediating activation of the p38/JNK pathway. This activation is mediated via their proteins binding and activating MTK1/MEKK4 kinase, which is an upstream activator of both p38 and JNK MAPKs. The function of these genes or their protein products is involved in the regulation of growth and apoptosis. These genes are regulated by different mechanisms, but they are often coordinately expressed and can function cooperatively in inhibiting cell growth. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.1) Tornatore, L., (2008) J. Mol. Biol. 378 (1), 97-111. |
| Immunogen | Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human GADD45B. |
| Clonality | Polyclonal |
|---|---|
| Host Species | Rabbit |
| Tested Applications | ELISAWB |
| GADD45B antibody can be used for detection of GADD45B by ELISA at 1:1562500. GADD45B antibody can be used for detection of GADD45B by western blot at 0.25 μg/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.: |
|
| Species Reactivity | HumanMouseRat |
| Concentration | 1mg/ml |
| Purification | Affinity purified |
| Gene Symbol | GADD45B |
|---|---|
| Alternative Names | GADD45B DKFZP566B133 GADD45BETA MYD118 |
| Molecular Weight(MW) | 18 kDa |
Application
Antibody used in IHC on Human Prostate Cancer at 2 ug/ml.
Application
Antibody used in IHC on Human Prostate Cancer at 2 ug/ml.
Application
Antibody used in IHC on Human Prostate Cancer at 2 ug/ml.
Application
Antibody used in WB on Human HepG2 at 0.2-1 ug/ml.| Positive Control | 1) Cat. No. 1211 - HepG2 Cell Lysate |
|---|---|
| Application Notes | GADD45B antibody can be used for detection of GADD45B by ELISA at 1:1562500. GADD45B antibody can be used for detection of GADD45B by western blot at 0.25 μg/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.: |
| Form | Liquid |
|---|---|
| Storage Instructions | For short periods of storage (days) store at 4˚C. For longer periods of storage, store GADD45B antibody at -20˚C. As with any antibody avoid repeat freeze-thaw cycles. |
| Storage Buffer | Antibody is lyophilized in PBS buffer with 2% sucrose. Add 50 μL of distilled water. Final antibody concentration is 1 mg/mL. |
