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GDF11 Antibody

Catalog Number:OM279648
OM279648
Discount Price
OM279648-100ul
1~2 Week
100ul
OM279648-50ul
50ul
OM279648-20ul
20ul
1~2 Week
Product Profile
Product Name GDF11 Antibody
Antibody Type Primary Antibodies
Product description GDF11 is a member of the bone morphogenetic protein (BMP) family and the TGF-beta superfamily. This group of proteins is characterized by a polybasic proteolytic processing site which is cleaved to produce a mature protein containing seven conserved cysteine residues. The members of this family are regulators of cell growth and differentiation in both embryonic and adult tissues. Studies in mice and Xenopus suggest that this protein is involved in mesodermal formation and neurogenesis during embryonic development.1) Lee, S.J., et al., Curr. Opin. Genet. Dev. 9(5):604-607 (1999).
Immunogen This GDF11 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 32-61 amino acids from the N-terminal region of human GDF11.
Key Feature
Clonality Polyclonal
Isotype Ig
Host Species Rabbit
Tested Applications IHC-PWB
For WB starting dilution is: 1:2000 For IHC-P starting dilution is: 1:10~50
Species Reactivity HumanMouse
Concentration 1mg/ml
Purification Affinity purified
Target Information
Gene Symbol GDF11
Alternative Names Growth/differentiation factor 11
GDF-11
Bone morphogenetic protein 11
BMP-11
GDF11
BMP11
Molecular Weight(MW) 45 kDa
Database Links
Entrez Gene 10220
Protein Accession O95390
Application

Application

Formalin-fixed and paraffin-embedded human colon carcinoma tissue reacted with GDF11 antibody , which was peroxidase-conjugated to the secondary antibody, followed by DAB staining.

Application

Formalin-fixed and paraffin-embedded human colon carcinoma tissue reacted with GDF11 antibody , which was peroxidase-conjugated to the secondary antibody, followed by DAB staining.

Application

Western Blot at 1:2000 dilution Lane 1: human heart lysate Lane 2: K562 whole cell lysate Lane 3: mouse kidney lysate Lane 4: 293 whole cell lysate Lane 5: Hela whole cell lysate Lane 5: mouse brain lysate Lysates/proteins at 20 ug per lane.
Application Notes For WB starting dilution is: 1:2000 For IHC-P starting dilution is: 1:10~50
Additional Information
Form Liquid
Storage Instructions Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Storage Buffer Supplied in PBS with 0.09% (W/V) sodium azide.
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