The protein encoded by this gene is a member of the GDNF
receptor family. It is a glycosylphosphatidylinositol(GPI)-linked
cell surface receptor for persephin, and mediates activation of the
RET tyrosine kinase receptor. This gene is a candidate gene for
RET-associated diseases. Alternatively spliced transcript variants
encoding different isoforms have been described for this gene.1) Yang, J., et al. FEBS Lett. 569 (1-3), 267-271 (2004) :
Immunogen
This GFRA4 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 156-184 amino acids from the Central region of human GFRA4.
Western blot analysis in HL-60,ZR-75-1,MDA-MB453 cell line lysates (35ug/lane).
Application Notes
For WB starting dilution is: 1:1000
Additional Information
Form
Liquid
Storage Instructions
Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.