Connexins are homologous four-transmembrane-domain proteins and major components of gap junctions. The GJB4 gene encodes connexin 30.3 (Cx30.3) A mutation in connexin 30.3 is causally involved in erythrokeratodermia variabilis (EKV), a mostly autosomal dominant disorder of keratinization.1) Plantard, L., et al., (2003) Hum. Mol. Genet. 12 (24), 3287-3294.
Immunogen
Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human GJB4.
Key Feature
Clonality
Polyclonal
Host Species
Rabbit
Tested Applications
ELISAWB
GJB4 antibody can be used for detection of GJB4 by ELISA at 1:1562500. GJB4 antibody can be used for detection of GJB4 by western blot at 1.25 μg/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.:
GJB4 antibody can be used for detection of GJB4 by ELISA at 1:1562500. GJB4 antibody can be used for detection of GJB4 by western blot at 1.25 μg/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.:
Additional Information
Form
Liquid
Storage Instructions
For short periods of storage (days) store at 4˚C. For longer periods of storage, store GJB4 antibody at -20˚C. As with any antibody avoid repeat freeze-thaw cycles.
Storage Buffer
IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.Store at -20 °C.Stable for 12 months from date of receipt