Application
Western blot analysis of lysed extracts from mouse brain and using GluR1 (phospho-Ser836).| Product Name | GluR1 (phospho Ser836) Antibody |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | GLUH1, GLUR1, GLURA, GluA1, HBGR1, P53, GLR1, GLUH1, GRIA1, GluR-1, GluR-A |
| Product description | Glutamate receptors are the predominant excitatory neurotransmitter receptors in the mammalian brain and are activated in a variety of normal neurophysiologic processes. These receptors are heteromeric protein complexes with multiple subunits, each possessing transmembrane regions, and all arranged to form a ligand-gated ion channel. The classification of glutamate receptors is based on their activation by different pharmacologic agonists. This gene belongs to a family of alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate (AMPA) receptors. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.1) Emamian ES, et al. (2004) J Neurosci. 24 (7): 1561-4Palmer, C. L. et al. (2005) Pharmacol. Rev. 57, 253-277. |
| Immunogen | GluR1 (phospho-Ser836) antibody was raised against a peptide sequence around phosphorylation site of serine 836 (S-E-Sp-K-R) derived from Human GluR1. |
| Modification | p-Ser836 |
| Clonality | Polyclonal |
|---|---|
| Host Species | Rabbit |
| Tested Applications | WB |
| Western Blot: 1:500~1:1000: |
|
| Species Reactivity | HumanMouseRat |
| Concentration | 1mg/ml |
| Purification | Affinity purified |
| Gene Symbol | GRIA1 |
|---|---|
| Alternative Names | GLUH1 GLUR1 GLURA GluA1 HBGR1 P53 GLR1 GLUH1 GRIA1 GluR-1 GluR-A |
| Molecular Weight(MW) | 110 kDa |
| Tissue Specificity | This antibody detects endogenous level of GluR1 only when phosphorylated at serine 836. |
| Entrez Gene | 2890 |
|---|---|
| Protein Accession | NP_000818.2 |
Application
Western blot analysis of lysed extracts from mouse brain and using GluR1 (phospho-Ser836).| Application Notes | Western Blot: 1:500~1:1000: |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | Store antibody at -20˚C for up to one year. |
| Storage Buffer | Antibody supplied in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
