Application
Western blot analysis of lysed extracts from mouse brain tissue using Glutamate receptor 2 (Precursor) (phospho-Ser880).| Product Name | Glutamate receptor 2 (Precursor) (phospho Ser880) Antibody |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | GLUR2, GLURB, GluA2, HBGR2, GluR-K2, PI12, GRIA2, GluR-2, GluR-B, AMPA 2 |
| Product description | Ionotropic glutamate receptor. L-glutamate acts as an excitatory neurotransmitter at many synapses in the central nervous system. Binding of the excitatory neurotransmitter L-glutamate induces a conformation change, leading to the opening of the cation channel, and thereby converts the chemical signal to an electrical impulse. The receptor then desensitizes rapidly and enters a transient inactive state, characterized by the presence of bound agonist.1) Cull-Candy, S. et al. (2006) Curr. Opin. Neurobiol. 16, 288-297. Hanley JG, et al. (2002) Neuron. 34 (1): 53-67 |
| Immunogen | Glutamate receptor 2 (Precursor) (phospho-Ser880) antibody was raised against a peptide sequence around phosphorylation site of serine 880 (I-E-S (p) -V-K) derived from Human Glutamate receptor 2. |
| Modification | p-Ser880 |
| Clonality | Polyclonal |
|---|---|
| Host Species | Rabbit |
| Tested Applications | WB |
| Western Blot: 1:500~1:1000: |
|
| Species Reactivity | HumanMouseRat |
| Concentration | 1mg/ml |
| Purification | Affinity purified |
| Gene Symbol | GRIA2 |
|---|---|
| Alternative Names | GLUR2 GLURB GluA2 HBGR2 GluR-K2 PI12 GRIA2 GluR-2 GluR-B AMPA 2 |
| Molecular Weight(MW) | 100 kDa |
| Tissue Specificity | This antibody detects endogenous level of Glutamate receptor 2 (Precursor) only when phosphorylated at serine 880. |
| Entrez Gene | 2891 |
|---|---|
| Protein Accession | NP_000817.2 |
Application
Western blot analysis of lysed extracts from mouse brain tissue using Glutamate receptor 2 (Precursor) (phospho-Ser880).| Application Notes | Western Blot: 1:500~1:1000: |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | Store antibody at -20˚C for up to one year. |
| Storage Buffer | Antibody supplied in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
