Golgi reassembly-stacking protein 1, Golgi peripheral membrane protein p65, Golgi phosphoprotein 5, GOLPH5, Golgi reassembly-stacking protein of 65 kDa, GRASP65, GORASP1, GOLPH5, GRASP65
Product description
The Golgi complex plays a key role in the sorting and
modification of proteins exported from the endoplasmic reticulum.
The protein encoded by this gene is a membrane protein involved in
establishing the stacked structure of the Golgi apparatus. It is a
caspase-3 substrate, and cleavage of this encoded protein
contributes to Golgi fragmentation in apoptosis. This encoded
protein can form a complex with the Golgi matrix protein GOLGA2,
and this complex binds to the vesicle docking protein p115. Several
alternatively spliced transcript variants of this gene have been
identified, but their full-length natures have not been determined.1) Bailey, S.D., et al. Diabetes Care 33(10):2250-2253(2010)
Immunogen
This GORASP1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 91-119 amino acids from the Central region of human GORASP1.
Western blot analysis in MCF-7 cell line lysates (35ug/lane).
Application Notes
For WB starting dilution is: 1:1000:
Additional Information
Form
Liquid
Storage Instructions
Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.