| Product Name | GPX3 Antibody |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | Glutathione Peroxidase 3 |
| Product description | Glutathione peroxidase 3 (GPX3; GSHPX3) is a selenium-dependent extracellular enzyme, protecting cells and enzymes from oxidative damage by catalyzing the reduction of hydrogen peroxide, lipid peroxides and organic hydroperoxides. GPX3 is involved in inflammatory bowel disease, in asthma and in diabetes. The activity of GPX3 is significantly reduced in the plasma and tissue of cancer patients. Recently, GPX3 was suggested to serve as a molecular marker for the diagnosis of clear cell type ovarian adenocarcinoma. |
| Immunogen | Recombinant mouse GPX3. |
| Clonality | Polyclonal |
|---|---|
| Host Species | Rabbit |
| Tested Applications | ELISAWB |
| ELISA: (direct and indirect: 1:2,000-1:5,000). Western Blot: (1:2,000-1:5,000 using ECL suggested blocking and dilution buffer is PBST containing 0.05% Tween 20 and 5% skim milk suggested incubation time is 1 hour at room temperature). Optimal conditions must be determined individually for each application.: |
|
| Species Reactivity | Mouse |
| Concentration | 1mg/ml |
| Gene Symbol | Gpx3 |
|---|---|
| Alternative Names | Glutathione Peroxidase 3 |
| Tissue Specificity | Recognizes mouse GPX3. Detects a band of ~20-27kDa by Western blot. Weakly cross-reacts with human GPX3. |
| Application Notes | ELISA: (direct and indirect: 1:2,000-1:5,000). Western Blot: (1:2,000-1:5,000 using ECL suggested blocking and dilution buffer is PBST containing 0.05% Tween 20 and 5% skim milk suggested incubation time is 1 hour at room temperature). Optimal conditions must be determined individually for each application.: |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | Stable for at least 6 months after receipt when stored at -20˚C. |
| Storage Buffer | Liquid. 0.2um-filtered solution in PBS, pH 7.4. Contains no preservatives. |
