This gene encodes a member of the GRB2/Sem5/Drk family.
This member is an adaptor-like protein involved in
leukocyte-specific protein-tyrosine kinase signaling. Like its
related family member, GRB2-related adaptor protein (GRAP), this
protein contains an SH2 domain flanked by two SH3 domains. This
protein interacts with other proteins, such as GRB2-associated
binding protein 1 (GAB1) and the SLP-76 leukocyte protein (LCP2),
through its SH3 domains. Transcript variants utilizing alternative
polyA sites exist.1) Rose, J.E., et al. Mol. Med. 16 (7-8), 247-253 (2010) :
Immunogen
This GRAP2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 131-159 amino acids from the Central region of human GRAP2.
GRB2-related adapter protein 2 Adapter protein GRID GRB-2-like protein GRB2L GRBLG GRBX Grf40 adapter protein Grf-40 Growth factor receptor-binding protein Hematopoietic cell-associated adapter protein GrpL P38 Protein GADS SH3-SH2-SH3 adapter
Western blot analysis in MCF-7 cell line lysates (35ug/lane).
Application Notes
For WB starting dilution is: 1:1000
Additional Information
Form
Liquid
Storage Instructions
Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.