Application
Immunohistochemistry staining of GSK3B in ovary tissue using GSK3B Antibody.| Product Name | GSK3B (phospho Ser9) Antibody |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | GSK3B, GSK-3 beta, GSK3 beta, GSK3beta, GSK3beta isoform, TPKI, GSK 3beta, Tau protein kinase I, ZGSK-3beta |
| Product description | Glycogen synthase kinase-3 (GSK 3) is a proline-directed serine-threonine kinase that was initially identified as a phosphorylating and inactivating glycogen synthase. Two isoforms, alpha (GSK 3A) and beta, show a high degree of amino acid homology. GSK 3B is involved in energy metabolism, neuronal cell development, and body pattern formation. GSK 3B participates in the Wnt signaling pathway and has been implicated in the hormonal control of several regulatory proteins including glycogen synthase, MYB and the transcription factor JUN. GSK 3B phosphorylates JUN at sites proximal to its DNA-binding domain, thereby reducing its affinity for DNA. |
| Immunogen | GSK3B antibody was raised against phospho amino acids 4 - 12 of GSK3B (Human). |
| Modification | p-Ser9 |
| Clonality | Polyclonal |
|---|---|
| Host Species | Rabbit |
| Tested Applications | ELISAIFIHCIPWB |
| GSK3B antibody can be used in ELISA starting at 1:15000 - 1:60000, Western Blot starting at 1:500 - 1:2000, and immunohistochemistry starting at 5 μg/mL.: |
|
| Species Reactivity | Human |
| Concentration | 1mg/ml |
| Purification | Affinity purified |
| Gene Symbol | GSK3B |
|---|---|
| Alternative Names | GSK3B GSK-3 beta GSK3 beta GSK3beta GSK3beta isoform TPKI GSK 3beta Tau protein kinase I ZGSK-3beta |
| Tissue Specificity | pSer9 |
Application
Immunohistochemistry staining of GSK3B in ovary tissue using GSK3B Antibody.| Application Notes | GSK3B antibody can be used in ELISA starting at 1:15000 - 1:60000, Western Blot starting at 1:500 - 1:2000, and immunohistochemistry starting at 5 μg/mL.: |
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| Form | Liquid |
|---|---|
| Storage Instructions | Store GSK3B antibody at 4 ˚C or -20 ˚C. As with all antibodies avoid freeze/thaw cycles. |
| Storage Buffer | 0.02 M potassium phosphate, 0.15 M sodium chloride, pH 7.2, 0.01% sodium azide. |
