General transcription factor II-I repeat domain-containing protein 1, GTF2I repeat domain-containing protein 1, General transcription factor III, MusTRD1/BEN, Muscle TFII-I repeat domain-containing protein 1, Slow-muscle-fiber enhancer-binding protein, USE
Product description
The protein encoded by this gene contains five GTF2I-like
repeats and each repeat possesses a potential helix-loop-helix
(HLH) motif. It may have the ability to interact with other
HLH-proteins and function as a transcription factor or as a
positive transcriptional regulator under the control of
Retinoblastoma protein. This gene plays a role in craniofacial and
cognitive development and mutations have been associated with
Williams-Beuren syndrome, a multisystem developmental disorder
caused by deletion of multiple genes at 7q11.23. Alternative
splicing results in multiple transcript variants. [provided by
RefSeq].1) Antonell, A., et al. J. Med. Genet. 47(5):312-320(2010)
Immunogen
This GTF2IRD1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 79-108 amino acids from the N-terminal region of human GTF2IRD1.
General transcription factor II-I repeat domain-containing protein 1 GTF2I repeat domain-containing protein 1 General transcription factor III MusTRD1/BEN Muscle TFII-I repeat domain-containing protein 1 Slow-muscle-fiber enhancer-binding protein USE
Western blot analysis in Hela cell line lysates (35ug/lane).
Application Notes
For WB starting dilution is: 1:1000:
Additional Information
Form
Liquid
Storage Instructions
Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.