Application
Antibody used in WB on Human MCF-7 at 0.2-1 ug/ml.| Product Name | GTSE1 Antibody |
|---|---|
| Antibody Type | Primary Antibodies |
| Product description | GTSE1 is only expressed in the S and G2 phases of the cell cycle, where it colocalizes with cytoplasmic tubulin and microtubules. In response to DNA damage, the encoded protein accumulates in the nucleus and binds the tumor suppressor protein p53, shuttling it out of the nucleus and repressing its ability to induce apoptosis.The protein encoded by this gene is only expressed in the S and G2 phases of the cell cycle, where it colocalizes with cytoplasmic tubulin and microtubules. In response to DNA damage, the encoded protein accumulates in the nucleus and binds the tumor suppressor protein p53, shuttling it out of the nucleus and repressing its ability to induce apoptosis.1) Beausoleil, S.A., (2006) Nat. Biotechnol. 24 (10), 1285-1292. |
| Immunogen | Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human GTSE1. |
| Clonality | Polyclonal |
|---|---|
| Host Species | Rabbit |
| Tested Applications | ELISAWB |
| GTSE1 antibody can be used for detection of GTSE1 by ELISA at 1:1562500. GTSE1 antibody can be used for detection of GTSE1 by western blot at 1 μg/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000. | |
| Species Reactivity | HumanMouseRat |
| Concentration | 1mg/ml |
| Purification | Affinity purified |
| Gene Symbol | GTSE1 |
|---|---|
| Alternative Names | GTSE1 B99 |
| Molecular Weight(MW) | 76 kDa |
Application
Antibody used in WB on Human MCF-7 at 0.2-1 ug/ml.| Positive Control | 1) Cat. No. 1219 - MCF7 Cell Lysate |
|---|---|
| Application Notes | GTSE1 antibody can be used for detection of GTSE1 by ELISA at 1:1562500. GTSE1 antibody can be used for detection of GTSE1 by western blot at 1 μg/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000. |
| Form | Liquid |
|---|---|
| Storage Instructions | For short periods of storage (days) store at 4˚C. For longer periods of storage, store GTSE1 antibody at -20˚C. As with any antibody avoid repeat freeze-thaw cycles. |
| Storage Buffer | Antibody is lyophilized in PBS buffer with 2% sucrose. Add 50 μL of distilled water. Final antibody concentration is 1 mg/mL. |
