Application
Western blot analysis in T47D cell line lysates (35ug/lane).Application
Western Blot at 1:2000 dilution Lane 1: T47D whole cell lysates Lane 2: KG-1 whole cell lysates Lane 3: human liver lysates Lysates/proteins at 20 ug per lane.Application
Western Blot at 1:2000 dilution Lane 1: T47D whole cell lysates Lane 2: human kidney lysates Lane 3: KG-1 whole cell lysates Lane 4: human liver lysates Lysates/proteins at 20 ug per lane.| Product Name | HAVCR2 Antibody |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | Hepatitis A virus cellular receptor 2, HAVcr-2, T-cell immunoglobulin and mucin domain-containing protein 3, TIMD-3, T-cell immunoglobulin mucin receptor 3, TIM-3, T-cell membrane protein 3, HAVCR2, TIM3, TIMD3 |
| Product description | CD4 (MIM 186940)-positive T helper lymphocytes can be divided into types 1 (Th1) and 2 (Th2) on the basis of their cytokine secretion patterns. Th1 cells and their associated cytokines are involved in cell-mediated immunity to intracellular pathogens and delayed-type hypersensitivity reactions, whereas Th2 cells are involved in the control of extracellular helminthic infections and the promotion of atopic and allergic diseases. The 2 types of cells also cross-regulate the functions of the other. TIM3 is a Th1-specific cell surface protein that regulates macrophage activation and enhances the severity of experimental autoimmune encephalomyelitis in mice.1) Cao, B., et al. Cancer Immunol. Immunother. 59(12):1851-1857(2010) |
| Immunogen | This HAVCR2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 167-194 amino acids from the Central region of human HAVCR2. |
| Clonality | Polyclonal |
|---|---|
| Isotype | Ig |
| Host Species | Rabbit |
| Tested Applications | WB |
| For WB starting dilution is: 1:2000: |
|
| Species Reactivity | Human |
| Concentration | 1mg/ml |
| Purification | Affinity purified |
| Gene Symbol | HAVCR2 |
|---|---|
| Alternative Names | Hepatitis A virus cellular receptor 2 HAVcr-2 T-cell immunoglobulin and mucin domain-containing protein 3 TIMD-3 T-cell immunoglobulin mucin receptor 3 TIM-3 T-cell membrane protein 3 HAVCR2 TIM3 TIMD3 |
| Molecular Weight(MW) | 33 kDa |
Application
Western blot analysis in T47D cell line lysates (35ug/lane).
Application
Western Blot at 1:2000 dilution Lane 1: T47D whole cell lysates Lane 2: KG-1 whole cell lysates Lane 3: human liver lysates Lysates/proteins at 20 ug per lane.
Application
Western Blot at 1:2000 dilution Lane 1: T47D whole cell lysates Lane 2: human kidney lysates Lane 3: KG-1 whole cell lysates Lane 4: human liver lysates Lysates/proteins at 20 ug per lane.| Application Notes | For WB starting dilution is: 1:2000: |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures. |
| Storage Buffer | Supplied in PBS with 0.09% (W/V) sodium azide. |
