Application
Western blot analysis of extracts from HepG2 tissue using HER2 (Phospho-Tyr1112) Antibody. The lane on the right is treated with the antigen-specific peptide.| Product Name | HER2 (phospho Tyr1112) Antibody |
|---|---|
| Antibody Type | Primary Antibodies |
| Product description | Essential component of a neuregulin-receptor complex, although neuregulins do not interact with it alone. GP30 is a potential ligand for this receptor. Not activated by EGF, TGF-alpha and amphiregulin.1) Chuang TD, et al. (2010)J Biol Chem 285, 23598-606 |
| Immunogen | HER2 (phospho Tyr1112) antibody was raised against a peptide sequence around phosphorylation site of tyrosine 1112 (Q-R-Y (p)-S-E) derived from Human HER2. |
| Modification | p-Tyr1112 |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | WB |
| Western Blot: 1:500~1:1000 | |
| Species Reactivity | HumanMouseRat |
| Concentration | 1mg/ml |
| Purification | Affinity purified |
| Gene Symbol | ERBB2 |
|---|---|
| Alternative Names | C-erbB-2 NGL NEU proto-oncogene MLN 19 |
| Molecular Weight(MW) | 150 kDa |
| Tissue Specificity | The antibody detects endogenous level of HER2 only when phosphorylated at tyrosine 1112. |
| Entrez Gene | 2064 |
|---|---|
| Protein Accession | NP_001005862.1 |
Application
Western blot analysis of extracts from HepG2 tissue using HER2 (Phospho-Tyr1112) Antibody. The lane on the right is treated with the antigen-specific peptide.| Application Notes | Western Blot: 1:500~1:1000 |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | Store antibody at -20˚C for up to one year. |
| Storage Buffer | Antibody supplied in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
