In vertebrates, the genes encoding the class of transcription factors called homeobox genes are found in clusters named A, B, C, and D on four separate chromosomes. Expression of these proteins is spatially and temporally regulated during embryonic development.HOXA2 is a DNA-binding transcription factor which may regulate gene expression, morphogenesis, and differentiateon. HOXA2 may be involved in the placement of hindbrain segments in the proper location along the anterior-posterior axis during development.In vertebrates, the genes encoding the class of transcription factors called homeobox genes are found in clusters named A, B, C, and D on four separate chromosomes. Expression of these proteins is spatially and temporally regulated during embryonic development. This gene is part of the A cluster on chromosome 7 and encodes a DNA-binding transcription factor which may regulate gene expression, morphogenesis, and differentiation. The encoded protein may be involved in the placement of hindbrain segments in the proper location along the anterior-posterior axis during development.1) Scherer, S.W., et al., (2003) Science 300 (5620), 767-772.
Immunogen
Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human HOXA2.
Key Feature
Clonality
Polyclonal
Host Species
Rabbit
Tested Applications
ELISAWB
HOXA2 antibody can be used for detection of HOXA2 by ELISA at 1:12500. HOXA2 antibody can be used for detection of HOXA2 by western blot at 0.5 μg/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.:
HOXA2 antibody can be used for detection of HOXA2 by ELISA at 1:12500. HOXA2 antibody can be used for detection of HOXA2 by western blot at 0.5 μg/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.:
Additional Information
Form
Liquid
Storage Instructions
For short periods of storage (days) store at 4˚C. For longer periods of storage, store HOXA2 antibody at -20˚C. As with any antibody avoid repeat freeze-thaw cycles.
Storage Buffer
Antibody is lyophilized in PBS buffer with 2% sucrose. Add 50 μL of distilled water. Final antibody concentration is 1 mg/mL.