This gene encodes a transcription factor that belongs to
the homeobox gene family. Genes of this family are highly conserved
among vertebrates and essential for vertebrate embryonic
development. This gene has been implicated to play a role in fetal
skin development and cutaneous regeneration. In mice, a similar
gene was shown to exhibit temporal and spatial colinearity in the
main body axis of the embryo, but was not expressed in the
secondary axes, which suggests functions in body patterning along
the axis. This gene and other HOXB genes form a gene cluster at
chromosome the 17q21-22 region.1) McMullin, R.P., et al. Proc. Natl. Acad. Sci. U.S.A. 107(1):98-103(2010)
Immunogen
This HOXB13 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 223-251 amino acids from the C-terminal region of human HOXB13.
Western blot analysis in mouse heart tissue lysates (35ug/lane).
Application Notes
For WB starting dilution is: 1:1000:
Additional Information
Form
Liquid
Storage Instructions
Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.