Application
immunohistochemistry analysis in formalin fixed and paraffin embedded human thyroid tissue followed by peroxidase conjugation of the secondary antibody and DAB staining.Application
Western blot analysis in mouse spleen tissue lysates (35ug/lane).This demonstrates the HTR2B antibody detected the HTR2B protein (arrow).Application
Western Blot at 1:2000 dilution Lane 1: human liver lysate Lane 2: human placenta lysate Lane 3: HT-29 whole cell lysate Lane 4: mouse heart lysate Lane 5: mouse spleen lysate Lane 5: rat stomach lysate Lysates/proteins at 20 ug per lane.| Product Name | HTR2B Antibody |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | 5-hydroxytryptamine receptor 2B, 5-HT-2B, 5-HT2B, Serotonin receptor 2B, HTR2B |
| Product description | Multiple receptor subtypes of serotonin neurotransmitters with multiple physiologic functions have been recognized. The 5-HT-2 receptors mediate many of the central and peripheral physiologic functions of serotonin. Cardiovascular effects include contraction of blood vessels and shape changes in platelets; central nervous system effects include neuronal sensitization to tactile stimuli and mediation of hallucinogenic effects of phenylisopropylamine hallucinogens.1) Bailey, S.D., et al. Diabetes Care 33(10):2250-2253(2010) Roberts, K.E., et al. Gastroenterology 139(1):130-139(2010) Svejda, B., et al. Cancer 116(12):2902-2912(2010) Talmud, P.J., et al. Am. J. Hum. Genet. 85(5):628-642(2009) Tabakoff, B., et al. BMC Biol. 7, 70 (2009) : |
| Immunogen | This HTR2B antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 408-435 amino acids from the C-terminal region of human HTR2B. |
| Clonality | Polyclonal |
|---|---|
| Isotype | Ig |
| Host Species | Rabbit |
| Tested Applications | IHC-PWB |
| For WB starting dilution is: 1:1000 For IHC-P starting dilution is: 1:10~50: |
|
| Species Reactivity | HumanMouseRat |
| Concentration | 1mg/ml |
| Purification | Affinity purified |
| Gene Symbol | HTR2B |
|---|---|
| Alternative Names | 5-hydroxytryptamine receptor 2B 5-HT-2B 5-HT2B Serotonin receptor 2B HTR2B |
| Molecular Weight(MW) | 54 kDa |
Application
immunohistochemistry analysis in formalin fixed and paraffin embedded human thyroid tissue followed by peroxidase conjugation of the secondary antibody and DAB staining.
Application
Western blot analysis in mouse spleen tissue lysates (35ug/lane).This demonstrates the HTR2B antibody detected the HTR2B protein (arrow).
Application
Western Blot at 1:2000 dilution Lane 1: human liver lysate Lane 2: human placenta lysate Lane 3: HT-29 whole cell lysate Lane 4: mouse heart lysate Lane 5: mouse spleen lysate Lane 5: rat stomach lysate Lysates/proteins at 20 ug per lane.| Application Notes | For WB starting dilution is: 1:1000 For IHC-P starting dilution is: 1:10~50: |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures. |
| Storage Buffer | Supplied in PBS with 0.09% (W/V) sodium azide. |
