Application
Antibody used in IHC on Human kidney.Application
Antibody used in WB on Human Jurkat 0.2-1 ug/ml.| Product Name | HTR3A Antibody |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | HTR3A, HTR3, 5HT3R, 5-HT-3, 5-HT3A, 5-HT3R |
| Product description | HTR3A belongs to the ligand-gated ion channel receptor superfamily. It is the subunit A of the type 3 receptor for 5-hydroxytryptamine (serotonin), a biogenic hormone that functions as a neurotransmitter, a hormone, and a mitogen. This receptor causes fast, depolarizing responses in neurons after activation. It appears that the heteromeric combination of A and B subunits is necessary to provide the full functional features of this receptor, since either subunit alone results in receptors with very low conductance and response amplitude. Alternatively spliced transcript variants encoding different isoforms have been identified.1) Panicker, S., et al., (2004) J. Biol. Chem. 279 (27), 28149-28158. |
| Immunogen | Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human HTR3A. |
| Clonality | Polyclonal |
|---|---|
| Host Species | Rabbit |
| Tested Applications | WB |
| HTR3A antibody can be used for detection of HTR3A by ELISA at 1:62500. HTR3A antibody can be used for detection of HTR3A by western blot at 1.0 μg/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.: |
|
| Species Reactivity | Human |
| Concentration | 1mg/ml |
| Purification | Affinity purified |
| Gene Symbol | HTR3A |
|---|---|
| Alternative Names | HTR3A HTR3 5HT3R 5-HT-3 5-HT3A 5-HT3R |
| Molecular Weight(MW) | 55 kDa |
Application
Antibody used in IHC on Human kidney.
Application
Antibody used in WB on Human Jurkat 0.2-1 ug/ml.| Positive Control | 1) Cat. No. 1205 - Jurkat Cell Lysate |
|---|---|
| Application Notes | HTR3A antibody can be used for detection of HTR3A by ELISA at 1:62500. HTR3A antibody can be used for detection of HTR3A by western blot at 1.0 μg/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.: |
| Form | Liquid |
|---|---|
| Storage Instructions | For short periods of storage (days) store at 4˚C. For longer periods of storage, store HTR3A antibody at -20˚C. As with any antibody avoid repeat freeze-thaw cycles. |
| Storage Buffer | Antibody is lyophilized in PBS buffer with 2% sucrose. Add 50 μL of distilled water. Final antibody concentration is 1 mg/mL. |
