Application
Western blot analysis in MDA-MB453,K562 cell line lysates (35ug/lane).| Product Name | HTR3A Antibody |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | 5-hydroxytryptamine receptor 3A, 5-HT3-A, 5-HT3A, 5-hydroxytryptamine receptor 3, 5-HT-3, 5-HT3R, Serotonin receptor 3A, Serotonin-gated ion channel receptor, HTR3A, 5HT3R, HTR3 |
| Product description | The product of this gene belongs to the ligand-gated ion channel receptor superfamily. This gene encodes subunit A of the type 3 receptor for 5-hydroxytryptamine (serotonin), a biogenic hormone that functions as a neurotransmitter, a hormone, and a mitogen. This receptor causes fast, depolarizing responses in neurons after activation. It appears that the heteromeric combination of A and B subunits is necessary to provide the full functional features of this receptor, since either subunit alone results in receptors with very low conductance and response amplitude. Alternatively spliced transcript variants encoding different isoforms have been identified.1) Gatt, J.M., et al. Biol. Psychiatry 68(9):818-824(2010) |
| Immunogen | This HTR3A antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 30-58 amino acids from the N-terminal region of human HTR3A. |
| Clonality | Polyclonal |
|---|---|
| Isotype | Ig |
| Host Species | Rabbit |
| Tested Applications | WB |
| For WB starting dilution is: 1:1000: |
|
| Species Reactivity | Human |
| Concentration | 1mg/ml |
| Purification | Affinity purified |
| Gene Symbol | HTR3A |
|---|---|
| Alternative Names | 5-hydroxytryptamine receptor 3A 5-HT3-A 5-HT3A 5-hydroxytryptamine receptor 3 5-HT-3 5-HT3R Serotonin receptor 3A Serotonin-gated ion channel receptor HTR3A 5HT3R HTR3 |
| Molecular Weight(MW) | 55 kDa |
Application
Western blot analysis in MDA-MB453,K562 cell line lysates (35ug/lane).| Application Notes | For WB starting dilution is: 1:1000: |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures. |
| Storage Buffer | Supplied in PBS with 0.09% (W/V) sodium azide. |
