The protein encoded by this gene is a member of the
intercellular adhesion molecule (ICAM) family. All ICAM proteins
are type I transmembrane glycoproteins, contain 2-9
immunoglobulin-like C2-type domains, and bind to the leukocyte
adhesion LFA-1 protein. This protein is constitutively and
abundantly expressed by all leucocytes and may be the most
important ligand for LFA-1 in the initiation of the immune
response. It functions not only as an adhesion molecule, but also
as a potent signalling molecule.1) Bailey, S.D., et al. Diabetes Care 33(10):2250-2253(2010)
Immunogen
This ICAM3 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 282-310 amino acids from the Central region of human ICAM3.
Western blot analysis in ZR-75-1 cell line lysates (35ug/lane).
Application Notes
For WB starting dilution is: 1:1000:
Additional Information
Form
Liquid
Storage Instructions
Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.