Application
Western blot analysis of extracts from Rat brain tissue using IGFBP-3 (Phospho-Ser183) Antibody. The lane on the right is treated with the antigen-specific peptide.| Product Name | IGFBP-3 (phospho Ser183) Antibody |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | IBP-3, IBP3, IGF-binding protein 3, IGFBP3, Insulin-like growth factor binding protein 3 precursor |
| Product description | IGF-binding proteins prolong the half-life of the IGFs and have been shown to either inhibit or stimulate the growth promoting effects of the IGFs on cell culture. They alter the interaction of IGFs with their cell surface receptors.1) Zhang Q, Steinle JJ (2013)Invest Ophthalmol Vis Sci 54, 3052-7 . Cobb LJ, Liu B, Lee KW, Cohen P (2006) Cancer Res 66, 10878-84 . |
| Immunogen | IGFBP-3 (phospho Ser183) antibody was raised against a peptide sequence around phosphorylation site of serine 183 (K-D-S (p)-Q-R) derived from Human IGFBP-3 . |
| Modification | p-Ser183 |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | WB |
| Western Blot: 1:500~1:1000: |
|
| Species Reactivity | HumanMouse |
| Concentration | 1mg/ml |
| Purification | Affinity purified |
| Gene Symbol | IGFBP3 |
|---|---|
| Alternative Names | IBP-3 IBP3 IGF-binding protein 3 IGFBP3 Insulin-like growth factor binding protein 3 precursor |
| Molecular Weight(MW) | 30 kDa |
| Tissue Specificity | The antibody detects endogenous level of IGFBP-3 only when phosphorylated at serine 183. |
| Entrez Gene | 3486 |
|---|---|
| Protein Accession | NP_000589.2 |
Application
Western blot analysis of extracts from Rat brain tissue using IGFBP-3 (Phospho-Ser183) Antibody. The lane on the right is treated with the antigen-specific peptide.| Application Notes | Western Blot: 1:500~1:1000: |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | Store antibody at -20˚C for up to one year. |
| Storage Buffer | Antibody supplied in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
