| Product Name | IL-24 Antibody |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | IL24, FISP, IL10B, IL-24, IL-4-induced secreted protein, Interleukin 24, Interleukin-24, Melanocyte-associated Mda-7, Mob-5, ST16, Mda-7, MDA7, MOB5, C49A |
| Product description | Interleukin 24 (IL-24)/melanoma differentiation-associated gene-7 (mda-7) encodes a secreted protein that exhibits significant homology to the interleukin 10 (IL-10) family of cytokines. The human IL-24 is secreted by activated peripheral blood mononuclear cells and binds two heterodimeric receptors, IL-22R1/IL-20R2 and IL-20R1/IL-20R2 resulting in the activation of JAK/STAT signaling pathways. Mda-7/IL-24, selectively induces growth suppression, apoptosis and radiosensitization in malignant gliomas in a p53-independent manner. |
| Immunogen | IL - 24 antibody was raised against a portion of amino acids 100 - 150 of IL - 24 (Human). |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | FACSIHCWB |
| IL-24 antibody can be used in ELISA starting at 1:2500 - 1:10000, Western Blot starting at 1:250 - 1:1000, immunohistochemistry starting at 5 μg/mL, immunocytochemistry, and immunofluorescence starting at 1:100 - 1:500.: |
|
| Species Reactivity | GorillaHumanMonkey |
| Concentration | 1mg/ml |
| Purification | Protein G |
| Gene Symbol | IL24 |
|---|---|
| Alternative Names | IL24 FISP IL10B IL-24 IL-4-induced secreted protein Interleukin 24 Interleukin-24 Melanocyte-associated Mda-7 Mob-5 ST16 Mda-7 MDA7 MOB5 C49A |
| Application Notes | IL-24 antibody can be used in ELISA starting at 1:2500 - 1:10000, Western Blot starting at 1:250 - 1:1000, immunohistochemistry starting at 5 μg/mL, immunocytochemistry, and immunofluorescence starting at 1:100 - 1:500.: |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | Store IL-24 antibody at 4 ˚C or -20 ˚C. As with all antibodies avoid freeze/thaw cycles. |
| Storage Buffer | PBS, 0.2% gelatin, 0.05% sodium azide. |
