The protein encoded by this gene is a protein
serine/threonine phosphatase of the PP2C family. This protein can
interact with integrin-linked kinase (ILK/ILK1), a regulator of
integrin mediated signaling, and regulate the kinase activity of
ILK. Through the interaction with ILK, this protein may selectively
affect the signaling process of ILK-mediated glycogen synthase
kinase 3 beta (GSK3beta), and thus participate in Wnt signaling
pathway.1) Nakrieko, K.A., et al. Cell Cycle 7(14):2157-2166(2008)
Immunogen
This ILKAP antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 93-122 amino acids from the Central region of human ILKAP.
Western blot analysis in U251 cell line lysates (35ug/lane).
Application Notes
For WB starting dilution is: 1:1000:
Additional Information
Form
Liquid
Storage Instructions
Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.