Application
Immunohistochemical analysis of paraffin-embedded human breast carcinoma tissue, using ITGB4 (Phospho-Tyr1510) antibody (left) or the same antibody preincubated with blocking peptide (right).| Product Name | ITGB4 (phospho Tyr1510) Antibody |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | GP150, ITB4, CD104 antigen |
| Product description | Integrin alpha-6/beta-4 is a receptor for laminin. Plays a critical structural role in the hemidesmosome of epithelial cells. Is required for the regulation of keratinocyte polarity and motility.1) Suzuki S., EMBO J. 9:757-763(1990). |
| Immunogen | ITGB4 (phospho Tyr1510) antibody was raised against a peptide sequence around phosphorylation site of tyrosine1510 (R-D-Y (p)-S-T) derived from Human ITGB4 . |
| Modification | p-Tyr1510 |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | IHC |
| Western Blot: 1:500~1:1000, Immunohistochemistry: 1:50~1:100: |
|
| Species Reactivity | MouseRat |
| Concentration | 1mg/ml |
| Purification | Affinity purified |
| Gene Symbol | ITGB4 |
|---|---|
| Alternative Names | GP150 ITB4 CD104 antigen |
| Molecular Weight(MW) | 202 kDa |
| Tissue Specificity | The antibody detects endogenous levels of ITGB4 only when phosphorylated at tyrosine 1510. |
| Entrez Gene | 3691 |
|---|---|
| Protein Accession | NP_000204.3 |
Application
Immunohistochemical analysis of paraffin-embedded human breast carcinoma tissue, using ITGB4 (Phospho-Tyr1510) antibody (left) or the same antibody preincubated with blocking peptide (right).| Application Notes | Western Blot: 1:500~1:1000, Immunohistochemistry: 1:50~1:100: |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | Store antibody at -20˚C for up to one year. |
| Storage Buffer | Antibody supplied in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
