Application
Antibody used in WB on Human Heart at 0.2-1 ug/ml.| Product Name | ITPK1 Antibody |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | ITPK1, ITRPK1 |
| Product description | ITPK1 is the kinase that can phosphorylate various inositol polyphosphate such as Ins (3,4,5,6)P4 or Ins (1,3,4)P3. It may also act as an isomerase that interconverts the inositol tetraphosphate isomers Ins (1,3,4,5)P4 and Ins (1,3,4,6)P4 in the presence of ADP and magnesium. It probably acts as the rate-limiting enzyme of the InsP6 pathway. ITPK1 modifies TNF-alpha-induced apoptosis by interfering with the activation of TNFRSF1A-associated death domain.1) Chamberlain, P.P., (2007) J. Biol. Chem. 282 (38), 28117-28125. |
| Immunogen | Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human ITPK1. |
| Clonality | Polyclonal |
|---|---|
| Host Species | Rabbit |
| Tested Applications | ELISAWB |
| ITPK1 antibody can be used for detection of ITPK1 by ELISA at 1:312500. ITPK1 antibody can be used for detection of ITPK1 by western blot at 1 μg/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.: |
|
| Species Reactivity | HumanMouseRat |
| Concentration | 1mg/ml |
| Purification | Affinity purified |
| Gene Symbol | ITPK1 |
|---|---|
| Alternative Names | ITPK1 ITRPK1 |
| Molecular Weight(MW) | 45 kDa |
Application
Antibody used in WB on Human Heart at 0.2-1 ug/ml.| Positive Control | 1) Cat. No. XBL-10407 - Fetal Heart Tissue Lysate |
|---|---|
| Application Notes | ITPK1 antibody can be used for detection of ITPK1 by ELISA at 1:312500. ITPK1 antibody can be used for detection of ITPK1 by western blot at 1 μg/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.: |
| Form | Liquid |
|---|---|
| Storage Instructions | For short periods of storage (days) store at 4˚C. For longer periods of storage, store ITPK1 antibody at -20˚C. As with any antibody avoid repeat freeze-thaw cycles. |
| Storage Buffer | Antibody is lyophilized in PBS buffer with 2% sucrose. Add 50 μL of distilled water. Final antibody concentration is 1 mg/mL. |
