Potassium channels are present in most mammalian cells, where they participate in a wide range of physiologic responses. KCNJ16 is an integral membrane protein and inward-rectifier type potassium channel. KCNJ16, which has a greater tendency to allow potassium to flow into a cell rather than out of a cell, can form heterodimers with two other inward-rectifier type potassium channels. It may be involved in the regulation of fluid and pH balance.Potassium channels are present in most mammalian cells, where they participate in a wide range of physiologic responses. The protein encoded by this gene is an integral membrane protein and inward-rectifier type potassium channel. The encoded protein, which has a greater tendency to allow potassium to flow into a cell rather than out of a cell, can form heterodimers with two other inward-rectifier type potassium channels. It may be involved in the regulation of fluid and pH balance. Three transcript variants encoding the same protein have been found for this gene.1) Ji, W., (2008) Nat. Genet. 40 (5), 592-599.
Immunogen
Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human KCNJ16.
Key Feature
Clonality
Polyclonal
Host Species
Rabbit
Tested Applications
WB
KCNJ16 antibody can be used for detection of KCNJ16 by ELISA at 1:12500. KCNJ16 antibody can be used for detection of KCNJ16 by western blot at 1 μg/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.:
Antibody used in WB on Human 721_B at 0.2-1 ug/ml.
Positive Control
1) 721_B Cell Lysate
Application Notes
KCNJ16 antibody can be used for detection of KCNJ16 by ELISA at 1:12500. KCNJ16 antibody can be used for detection of KCNJ16 by western blot at 1 μg/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.:
Additional Information
Form
Liquid
Storage Instructions
For short periods of storage (days) store at 4˚C. For longer periods of storage, store KCNJ16 antibody at -20˚C. As with any antibody avoid repeat freeze-thaw cycles.
Storage Buffer
Antibody is lyophilized in PBS buffer with 2% sucrose. Add 50 μL of distilled water. Final antibody concentration is 1 mg/mL.