Application
Western Blot at 1:2000 dilution Lane 1: Raji whole cell lysate Lane 2: Hela whole cell lysate Lane 3: Daudi whole cell lysate Lane 4: HT-29 whole cell lysate Lane 5: NIH/3T3 whole cell lysate Lysates/proteins at 20 ug per lane.Application
Antibody staining KHDRBS1 in human colorectal carcinoma tissue sections by Immunohistochemistry (IHC-P - paraformaldehyde-fixed, paraffin-embedded sections).Application
Antibody staining KHDRBS1 in human colorectal carcinoma tissue sections by Immunohistochemistry (IHC-P - paraformaldehyde-fixed, paraffin-embedded sections).| Product Name | KHDRBS1 Antibody |
|---|---|
| Antibody Type | Primary Antibodies |
| Product description | Recruited and tyrosine phosphorylated by several receptor systems, for example the T-cell, leptin and insulin receptors. Once phosphorylated, functions as an adapter protein in signal transduction cascades by binding to SH2 and SH3 domain- containing proteins. Role in G2-M progression in the cell cycle. Represses CBP-dependent transcriptional activation apparently by competing with other nuclear factors for binding to CBP. Also acts as a putative regulator of mRNA stability and/or translation rates and mediates mRNA nuclear export. Positively regulates the association of constitutive transport element (CTE)-containing mRNA with large polyribosomes and translation initiation. According to some authors, is not involved in the nucleocytoplasmic export of unspliced (CTE)-containing RNA species according to (PubMed: 22253824 ).1) Wong G.,et al.Cell 69:551-558(1992). |
| Immunogen | This KHDRBS1 antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 259-291 amino acids from the Central region of human KHDRBS1. |
| Clonality | Polyclonal |
|---|---|
| Isotype | Ig |
| Host Species | Rabbit |
| Tested Applications | IHC-PWB |
| For IHC-P starting dilution is: 1:25 For WB starting dilution is: 1:2000 | |
| Species Reactivity | HumanMouse |
| Concentration | 1mg/ml |
| Purification | Affinity purified |
| Gene Symbol | KHDRBS1 |
|---|---|
| Alternative Names | KH domain-containing RNA-binding signal transduction-associated protein 1 GAP-associated tyrosine phosphoprotein p62 Src-associated in mitosis 68 kDa protein Sam68 p21 Ras GTPase-activating protein-associated p62 p68 KHDRBS1 ( HGNC:18116 ) |
| Molecular Weight(MW) | 48 kDa |
Application
Western Blot at 1:2000 dilution Lane 1: Raji whole cell lysate Lane 2: Hela whole cell lysate Lane 3: Daudi whole cell lysate Lane 4: HT-29 whole cell lysate Lane 5: NIH/3T3 whole cell lysate Lysates/proteins at 20 ug per lane.
Application
Antibody staining KHDRBS1 in human colorectal carcinoma tissue sections by Immunohistochemistry (IHC-P - paraformaldehyde-fixed, paraffin-embedded sections).
Application
Antibody staining KHDRBS1 in human colorectal carcinoma tissue sections by Immunohistochemistry (IHC-P - paraformaldehyde-fixed, paraffin-embedded sections).| Application Notes | For IHC-P starting dilution is: 1:25 For WB starting dilution is: 1:2000 |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures. |
| Storage Buffer | Supplied in PBS with 0.09% (W/V) sodium azide. |
