This gene encodes a hematopoietic-specific transcription
factor that induces high-level expression of adult beta-globin and
other erythroid genes. The zinc-finger protein binds to the DNA
sequence CCACACCCT found in the beta hemoglobin promoter.
Heterozygous loss-of-function mutations in this gene result in the
dominant In(Lu) blood phenotype.1) Borg, J., et al. Nat. Genet. 42(9):801-805(2010)
Immunogen
This KLF1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 248-276 amino acids from the C-terminal region of human KLF1.
Western blot analysis in NCI-H292 cell line lysates (35ug/lane).
Application Notes
For WB starting dilution is: 1:1000
Additional Information
Form
Liquid
Storage Instructions
Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.