| Product Name | LAG-3 Antibody |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | Lymphocyte Activation Gene-3; FDC Protein; CD223 |
| Product description | Lymphocyte activation gene 3 (LAG-3; CD223) plays an important role in negatively regulating T cell proliferation, function and homeostasis. It is required for maximal natural and induced regulatory T cell (Treg) function. LAG-3 is closely related to the T cell co-receptor CD4 and binds to MHC class II molecules but with a significantly higher affinity than CD4. |
| Immunogen | Synthetic peptide corresponding to 30 aa in the N-terminus of human LAG-3. |
| Clonality | Monoclonal |
|---|---|
| Isotype | IgG1 |
| Host Species | Mouse |
| Tested Applications | FunctionalStudiesICCIHCIPWB |
| Immunohistochemistry: (EM). Immunoprecipitation: (1-2ug/ml) . Western Blot: (1-5ug/ml) . Optimal conditions must be determined individually for each application.: |
|
| Species Reactivity | Human |
| Concentration | 1mg/ml |
| Purification | Affinity purified |
| Gene Symbol | LAG3 |
|---|---|
| Alternative Names | Lymphocyte Activation Gene-3 FDC Protein CD223 |
| Tissue Specificity | Recognizes human LAG-3. |
| Application Notes | Immunohistochemistry: (EM). Immunoprecipitation: (1-2ug/ml) . Western Blot: (1-5ug/ml) . Optimal conditions must be determined individually for each application.: |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | Stable for at least 1 year after receipt when stored at -20˚C. |
| Storage Buffer | Liquid. In PBS containing 10% glycerol and 0.02% sodium azide. |
Data sheet for OM283192